Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Assessment of Portal Vein Thrombosis and Associated Factors Among Patients Admitted to Tibebe Ghion Hospital Medical Ward, Hepatology Unit, Bahir Dar, Ethiopia, A Cross-sectional Study, 2025
View through CrossRef
Abstract
Background
Portal vein thrombosis (PVT) is a Liver vascular disease characterized by the development of a blood clot inside the portal vein's main branches or trunk. There is limited study on PVT and associated factors in Africa even with no study from Ethiopia. Therefore, this study was conducted to assess the prevalence of portal vein thrombosis and associated factors among patients at TGSH medical ward hepatology unit, Bahirdar, Ethiopia from January 1, 2021 to December 31, 2024.
Method
A retrospective Cross-sectional study design was conducted from January 1, 2021 to December 31, 2024, at Tibebe Ghion Specialized Hospital. A simple random sampling technique was used to select a total of 422 patients. The Data was collected using structured interviewer-administered questionnaires and a checklist for document review. Data was coded and entered into EpiData version 4.6 and exported into SPSS version 25 for analysis. Bivariate and multivariable logistic regression were used to identify factors associated with PVT at 95% confidence interval. The ethical clearance was obtained from the Institutional Review Board of the College of Medicine and Health Sciences of Bahir Dar University.
Result
A total of 407 study subjects were included, and 64 (15.7%) had portal vein thrombosis. Having a diagnosis of CLD, the AOR is 2.139 (95% CI: 1.017–4.499) with a p-value of 0.045, patients with HCC with an AOR of 3.912 (95% CI: 1.609–9.512) and a significant p-value of 0. 003. Platelet count > 450K, with an AOR of 4.574 (95% CI: 1.989–10.519) and a p-value of 0.001 were significantly associated with portal vein thrombosis.
Conclusion and Recommendations:
This study found a high prevalence of PVT among hospitalized patients, while CLD, HCC and elevated platelets significantly increasing risk. Future research should explore causal factors, thrombophilia, and broader patient groups for better prevention.
Springer Science and Business Media LLC
Title: Assessment of Portal Vein Thrombosis and Associated Factors Among Patients Admitted to Tibebe Ghion Hospital Medical Ward, Hepatology Unit, Bahir Dar, Ethiopia, A Cross-sectional Study, 2025
Description:
Abstract
Background
Portal vein thrombosis (PVT) is a Liver vascular disease characterized by the development of a blood clot inside the portal vein's main branches or trunk.
There is limited study on PVT and associated factors in Africa even with no study from Ethiopia.
Therefore, this study was conducted to assess the prevalence of portal vein thrombosis and associated factors among patients at TGSH medical ward hepatology unit, Bahirdar, Ethiopia from January 1, 2021 to December 31, 2024.
Method
A retrospective Cross-sectional study design was conducted from January 1, 2021 to December 31, 2024, at Tibebe Ghion Specialized Hospital.
A simple random sampling technique was used to select a total of 422 patients.
The Data was collected using structured interviewer-administered questionnaires and a checklist for document review.
Data was coded and entered into EpiData version 4.
6 and exported into SPSS version 25 for analysis.
Bivariate and multivariable logistic regression were used to identify factors associated with PVT at 95% confidence interval.
The ethical clearance was obtained from the Institutional Review Board of the College of Medicine and Health Sciences of Bahir Dar University.
Result
A total of 407 study subjects were included, and 64 (15.
7%) had portal vein thrombosis.
Having a diagnosis of CLD, the AOR is 2.
139 (95% CI: 1.
017–4.
499) with a p-value of 0.
045, patients with HCC with an AOR of 3.
912 (95% CI: 1.
609–9.
512) and a significant p-value of 0.
003.
Platelet count > 450K, with an AOR of 4.
574 (95% CI: 1.
989–10.
519) and a p-value of 0.
001 were significantly associated with portal vein thrombosis.
Conclusion and Recommendations:
This study found a high prevalence of PVT among hospitalized patients, while CLD, HCC and elevated platelets significantly increasing risk.
Future research should explore causal factors, thrombophilia, and broader patient groups for better prevention.
Related Results
One in Twenty-five Patients is suffering from Deep Vein Thrombosis in Tibebe Ghion Specialized Hospital Bahir Dar, North West Ethiopia
One in Twenty-five Patients is suffering from Deep Vein Thrombosis in Tibebe Ghion Specialized Hospital Bahir Dar, North West Ethiopia
Abstract
Background:
Trauma leads to significant physiologic changes that result in patients at elevated risk for thromboemboli...
One in Twenty-five Patients is suffering from Deep Vein Thrombosis in Tibebe Ghion Specialized Hospital Bahir Dar, North West Ethiopia
One in Twenty-five Patients is suffering from Deep Vein Thrombosis in Tibebe Ghion Specialized Hospital Bahir Dar, North West Ethiopia
Abstract
Background:
Trauma leads to significant physiologic changes that result in patients at elevated risk for thromboemboli...
The Prevalence of JAK2 Mutation in High-Altitude Patients with Unprovoked Thrombosis and Thrombosis at Unusual Sites
The Prevalence of JAK2 Mutation in High-Altitude Patients with Unprovoked Thrombosis and Thrombosis at Unusual Sites
Introduction
Thrombosis, both arterial and venous, is a major source of morbidity and mortality in patients with myeloproliferative neoplasms (MPNs). Thrombosis can ...
Venous Thromboembolism in Denmark: Seasonality in Occurrence and Mortality
Venous Thromboembolism in Denmark: Seasonality in Occurrence and Mortality
Background Many cardiovascular conditions exhibit seasonality in occurrence and mortality, but little is known about the seasonality of venous thromboembolism.
Methods ...
The Impact of IL28B Gene Polymorphisms on Drug Responses
The Impact of IL28B Gene Polymorphisms on Drug Responses
To achieve high therapeutic efficacy in the patient, information on pharmacokinetics, pharmacodynamics, and pharmacogenetics is required. With the development of science and techno...
Non-Cirrhotic Splanchnic Vein Thrombosis: When Is Anticoagulation Enough?
Non-Cirrhotic Splanchnic Vein Thrombosis: When Is Anticoagulation Enough?
Abstract
Abstract 3390
Background:
In the absence of primary liver disease, thrombosis of the splanchnic vessels ...
Proportion and associated factors of meconium aspiration syndrome in neonates admitted to NICU Tibebe Ghion Specialized Hospital Bahir Dar Amhara Reginal State North West Ethiopia, 2025
Proportion and associated factors of meconium aspiration syndrome in neonates admitted to NICU Tibebe Ghion Specialized Hospital Bahir Dar Amhara Reginal State North West Ethiopia, 2025
Abstract
Back ground: Meconium aspiration syndrome is defined as respiratory distress in newborn infant born through meconium-stained amniotic fluid whose symptoms can’t be explai...
PORTAL VEIN THROMBOSIS – A STUDY OF RISK FACTORS, CLINICAL PROFILE, COMPLICATIONS AND MANAGEMENT
PORTAL VEIN THROMBOSIS – A STUDY OF RISK FACTORS, CLINICAL PROFILE, COMPLICATIONS AND MANAGEMENT
Background: The portal vein is formed by the conuence of the splenic and superior mesenteric veins. Occlusion of the portal vein by thrombus
(portal vein thrombosis [PVT]) typical...