Evaluation of anterior scleral thickness in eyes with central serous chorioretinopathy

Purpose: To compare the anterior scleral thickness in eyes with central serous chorioretinopathy (CSC) and healthy eyes. Design: Cross-sectional observational study. Methods: The study included patients with CSC and age and gender-matched healthy individuals. The subfoveal choroidal thickness (SFCT) and scleral thickness at 3 mm, 4 mm, and 8 mm posterior to the scleral spur were measured using swept source optical coherence tomography (Topcon DRI-OCT Triton plus). Results: The study included 35 eyes with CSC and 35 control eyes. In CSC group, 82.86% were simple and 17.14% were complex. There was no statistically significant difference in the scleral thickness in CSC and control groups. Though the sclera was thicker in the complex CSC group compared to simple CSC at 3 mm (nasal: 724.33 ± 180.53 vs 658.48 ± 57.63, temporal: 696.17 ± 212.91 vs 628.83 ± 107.7) and 4 mm (nasal: 656.67 ± 109.34 vs 621.62 ± 79.31, temporal: 640.17 ± 191.31 vs 616.48 ± 86.30), the difference was not statistically significant. A moderate negative correlation was noted between SFCT and scleral thickness at 8 mm (r -0.349) and 3 mm on the nasal side (r -0.388) in the control group. A moderate negative correlation was noted between SFCT and scleral thickness at 4 mm (r -0.377) and 3 mm (r -0.403) on the temporal side in CSC group. Conclusion: The anterior scleral thickness was similar in CSC and healthy eyes. As the study sample predominantly included simple CSC, the findings indicate that the anterior scleral thickness may not be involved in the pathogenesis of simple CSC.