Standardized Clinical Protocol for 650 nm and 810 nm Diode Laser Photobiomodulation After Dental Implant Placement v1

This protocol describes a randomized controlled clinical procedure for evaluating the analgesic effects of photobiomodulation using 650 nm and 810 nm diode lasers following dental implant placement in the posterior maxilla. The procedure standardizes surgical parameters, laser irradiation settings, treatment schedules, and outcome assessments, including postoperative pain, analgesic intake, and oral health–related quality of life. Expected outcomes include reduced postoperative pain intensity and decreased analgesic consumption in active photobiomodulation groups compared with sham treatment. The protocol is designed to support reproducibility and transparent reporting of laser-assisted pain management following implant surgery. Developed in accordance with SPIRIT guidelines for interventional protocols, this document underpins the randomized controlled trial “Analgesic outcomes of 650 nm versus 810 nm diode laser photobiomodulation after dental implant placement,” which has been accepted for publication in Scientific Reports. The study adheres to CONSORT recommendations and is registered at ClinicalTrials.gov (Identifier: NCT06988722). A preprint version is available on Research Square (DOI: 10.21203/rs.3.rs-6858207/v1).