Research Progress on Modeling Methods of TCM Syndromes in Experimental Animals

TCM syndrome is the core of TCM treatment based on syndrome differentiation. Modeling of TCM syndromes in experimental animals is an important bridge connecting TCM basic theory and modern medical research, and also a key technical support for carrying out TCM efficacy evaluation, pathogenesis exploration, and new drug research and development. With the continuous advancement of TCM modernization, the modeling technology of TCM syndromes in experimental animals has been gradually improved, and the modeling methods have shown a trend of diversification, standardization and refinement. This article systematically sorts out the basic principles and core modeling methods of TCM syndrome modeling in experimental animals, focuses on reviewing the specific modeling technologies, application status and research hotspots of common clinical TCM syndromes (such as qi deficiency syndrome, blood deficiency syndrome, yin deficiency syndrome, yang deficiency syndrome, phlegm-dampness syndrome, blood stasis syndrome, etc.), analyzes the existing problems in the current modeling process (such as inconsistent modeling standards, insufficient syndrome stability, imperfect evaluation system, etc.), and looks forward to the development direction of modeling technology in the future, so as to provide a reference for the standardized application of experimental animal syndrome modeling in TCM basic research.