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Analytical and bioanalytical perspectives on doxazosin for biosciences and therapeutic research
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Doxazosin, a selective antagonist of alpha-1 adrenergic receptor which is commonly applied for curing hypertension and benign prostatic hyperplasia. For pharmaceutical quality control and efficient treatment monitoring, doxazosin estimation in biological fluids must be done precisely. Numerous analytical and bioanalytical techniques developed for its detection are integrated in this comprehensive study, including spectrophotometric techniques, electrophoretic approaches, and chromatographic techniques (HPLC, UPLC, and LC-MS/MS). In the current study overview of doxazocin and its pharmaceutical significance along with physicochemical properties, analytical and bioanalytical methods, recent developments that improve analytical performance, bioanalytical method validation, various validation parameters are highlighted. This review provides a comparative evaluation of different methods, emphasising their benefits, drawbacks, and suitability for use in various academic, professional and industrial contexts.
Rishan Publications
Title: Analytical and bioanalytical perspectives on doxazosin for biosciences and therapeutic research
Description:
Doxazosin, a selective antagonist of alpha-1 adrenergic receptor which is commonly applied for curing hypertension and benign prostatic hyperplasia.
For pharmaceutical quality control and efficient treatment monitoring, doxazosin estimation in biological fluids must be done precisely.
Numerous analytical and bioanalytical techniques developed for its detection are integrated in this comprehensive study, including spectrophotometric techniques, electrophoretic approaches, and chromatographic techniques (HPLC, UPLC, and LC-MS/MS).
In the current study overview of doxazocin and its pharmaceutical significance along with physicochemical properties, analytical and bioanalytical methods, recent developments that improve analytical performance, bioanalytical method validation, various validation parameters are highlighted.
This review provides a comparative evaluation of different methods, emphasising their benefits, drawbacks, and suitability for use in various academic, professional and industrial contexts.
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