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Role of Keratinases in Dermatophytosis

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The capillary tube migration test was used for the ‘in vitro’ demonstration of delayed hypersensistivity to two keratinases isolated from T. Mentagrophytes var. granulosum. Both heat-inactivated keratinases, I and II, inhibited migration of peritoneal exudate cells from guinea pigs previously infected twice with this dermatophyte. Trichophytin did not cause any significant inhibition of migration.
Title: Role of Keratinases in Dermatophytosis
Description:
The capillary tube migration test was used for the ‘in vitro’ demonstration of delayed hypersensistivity to two keratinases isolated from T.
Mentagrophytes var.
granulosum.
Both heat-inactivated keratinases, I and II, inhibited migration of peritoneal exudate cells from guinea pigs previously infected twice with this dermatophyte.
Trichophytin did not cause any significant inhibition of migration.

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