Bioinformatics and synteny analysis of “gecko gecko” as an evolutionary conserved social group habitable than other genera

Abstract BACKGROUND: Gecko, a reptile distinguishable by its heterogeneity and quiescent features, has been evolutionary marginalized as increased constraints are characterized to a particular species of the Gekkonidae (Hemidactylus frenatus), but more exploited is the species endemic to West Africa (Ancylodactylus africanus), which has the least conservative propensity. This study incorporates the use of integrative approaches coupled with bioinformatics tools to analyze and provide possible insights and answers to the puzzling questions of red zoned (endangered species) organisms extinction attenuated by a sporadic increase in anthropogenic cum socio-cultural norms posing death and elimination of such species. RESULTS: RAG1 gene, confers heterogeneity to gecko. The molecular function of mitochondrial cytochrome C oxidase in reptiles has not been identified but interesting it is observed that sequences conserved across species are highly similar but with single nucleotide substitution differentiating specific reptile as the snake, prospective studies should be carried to identify the function through genetic engineering. Sociocultural norms can affect the availability of organisms’ endemic in a geographical location and can inversely affect the ecosystem pool. Evidence based on the secondary data gathered shows that,42% and 58% accounted to quiet nature, and socially habitable nature of wall gecko compared with lizards respectively. However, 44% accounted to anthropological factors that endangers gecko which is inclusive of sociocultural norms and belief system. Moreover, 67% do not believe in any traditional or socio-cultural ideology related to the Wall gecko but 33% believe in traditional or socio-cultural ideology related to the Wall gecko. This raises concerns on the argument of cultural norms influencing the availability of species and can result in extinction over time. CONCLUSIONS: The findings revealed that Gecko is more socially habitable than the lizards but endangered and prone to extinction by anthroplological factors which is inclusive but not limited to sociocultural norms and belief. The study further suggest that insights in the molecular function of mitochondrial cytochrome C oxidase gene in reptiles can be unveiled through the single nucletide substitution specific to the snakes which distinguishes the sequence from other closely related reptilia. This can further be investigated through genetic engineering.