The use of cyanoacrylate – based biological adhesives for tympanum graft fixation during tympanoplasty

The objective of this work was to improve the functional outcomes of treatment the patients with chronic purulent otitis media by application of cyanoacrylate-based biological adhesive for fixation of the tympanic membrane graft during tympanoplasty. For our study we selected 125 patients with chronic suppurative otitis media. In all cases, the patients were performed a closed type sanitizing operation (separate atticoantrotomy) with some type of tympanoplasty. A temporal muscle fascia was used as neotympanic graft. In the main group neotympanic membrane was strengthened by means of cyanoacrylate-based biological adhesive. In the control group, the operations were performed without the bioadhesive. The evaluation of the morphological and functional results of the operation was performed in 1, 3 and 12 months using otomicroscopy, pneumatic otoendoscopy and tonal threshold audiometry. The study revealed that the use of cyanoacrylate-based biological adhesive in tympanoplasty reduces the risk of neotympanic membrane displacement in the postoperative period before the generation of physiological fixation due to the middle ear tissue regeneration.