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Peak Intraocular Pressure Time during Water Drinking Test and Its Relationship with Glaucoma Severity

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Purpose: To investigate the association between the time of occurrence of intraocular pressure (IOP) peaks during the water-drinking test (WDT) and visual field damage in a cohort of primary open-angle glaucoma (POAG) patients. Methods: In this retrospective, cross-sectional study, 98 eyes from 49 consecutive POAG patients were followed in a referral clinical practice. The relationship between the time when IOP peaks occurred during the WDT and the visual field mean deviation (MD) assessed with 24-2 visual field was tested with mixed-effects models. Results: MD value was significantly associated with the time of IOP peak occurrence (P = 0.020) when adjusting for the number of medications, but not with the IOP peak values (P = 0.238). Conclusion: The time of IOP peaks occurrence during the WDT was associated with glaucoma severity among treated POAG patients.
Title: Peak Intraocular Pressure Time during Water Drinking Test and Its Relationship with Glaucoma Severity
Description:
Purpose: To investigate the association between the time of occurrence of intraocular pressure (IOP) peaks during the water-drinking test (WDT) and visual field damage in a cohort of primary open-angle glaucoma (POAG) patients.
Methods: In this retrospective, cross-sectional study, 98 eyes from 49 consecutive POAG patients were followed in a referral clinical practice.
The relationship between the time when IOP peaks occurred during the WDT and the visual field mean deviation (MD) assessed with 24-2 visual field was tested with mixed-effects models.
Results: MD value was significantly associated with the time of IOP peak occurrence (P = 0.
020) when adjusting for the number of medications, but not with the IOP peak values (P = 0.
238).
Conclusion: The time of IOP peaks occurrence during the WDT was associated with glaucoma severity among treated POAG patients.

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