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IRIDOID GLUCOSIDES FROM <i>Barleria lupulina</i> LINDL.
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Four iridoid glycosides, 6-O-trans-p-coumaroyl-8-O-acetylshanzhiside methyl ester (1), 6-O-p-methoxy-trans-cinnamoyl-8-O-acetylshanzhiside methyl ester (2), 6-O-cis-p-coumaroylshanzhiside methyl ester (3), and ipolamiide (4) have been purified and structurally elucidated from Barleria lupulina Lindl. (Acanthaceae) collected in Luang Namtha province, Laos. Compound 1, at a concentration of 128 μg/mL, inhibited the growth of the A549 cancer cell line by 31% and nitric oxide production in RAW 264.7 cells by 30%. This is the first report on the chemical constituents of Lao’s Barleria lupulina.
Journal of Science, Hanoi National University of Education
Title: IRIDOID GLUCOSIDES FROM <i>Barleria lupulina</i> LINDL.
Description:
Four iridoid glycosides, 6-O-trans-p-coumaroyl-8-O-acetylshanzhiside methyl ester (1), 6-O-p-methoxy-trans-cinnamoyl-8-O-acetylshanzhiside methyl ester (2), 6-O-cis-p-coumaroylshanzhiside methyl ester (3), and ipolamiide (4) have been purified and structurally elucidated from Barleria lupulina Lindl.
(Acanthaceae) collected in Luang Namtha province, Laos.
Compound 1, at a concentration of 128 μg/mL, inhibited the growth of the A549 cancer cell line by 31% and nitric oxide production in RAW 264.
7 cells by 30%.
This is the first report on the chemical constituents of Lao’s Barleria lupulina.
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