Correlation analysis between sleep quality and dyslipidemia in the elderly

Abstract Background: To provide a scientific basis for the early prevention of dyslipidemia, we investigate the relationship between sleep quality and dyslipidemia in the elderly. Methods: The survey subjects for questionnaires, physical measurements, and laboratory tests were permanent residents aged 65 years and older in a community who participated in physical examination at the Public Health Management Center of Zuoyun County Medical Group in Shanxi Province from August 2020 to September 2020. Questionnaires were used to collect the demographic characteristics and sleep status of the survey subjects to measure height, weight, and blood pressure; to collect fasting venous blood; and to determine total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C). The association between sleep quality and dyslipidemia was determined by binary logistic regression models. Age, gender, current smoking, current drinking, obesity, and hypertension were adjusted as confounders. Odds-ratio (OR) with corresponding 95% confidence intervals (CI) were reported as effect measurements. Results: In 292 study subjects aged 65–92 (71.8 ± 5.1) years, the proportion of sleep disorders in the elderly was 40.4%, and the detection rate of dyslipidemia was 45.9%. The prevalence rates of abnormal TC, abnormal TG, and dyslipidemia were 27.1%, 28.0%, and 53.4%, respectively, in those with sleep disorders, which were significantly higher than those in those without sleep disorders (13.2%, 17.2%, and 40.8%, respectively). After further adjustment for age, gender, smoking, drinking, hypertension, and obesity, the aforementioned phenomena persisted, and having sleep disorders was a risk factor for abnormal TC [OR (95% CI) = 2.204 (1.160–4.190)], abnormal TG [OR (95% CI) = 1.904 (1.025–3.535)], and dyslipidemia [OR (95% CI = 1.741 (1.046–2.898)] (P < 0.05). Conclusions: Sleep quality in the elderly is strongly associated with the prevalence of abnormal TC, abnormal TG, and dyslipidemia, and sleep disorders may increase the risk of developing dyslipidemia.