Maculopathy associated with angioid streaks

Abstract Purpose To present choroidal neovascularization and macular atrophy without neovascularization associated with angioid streaks by means of two case reports. Methods Two middle aged man (42 an 46 years old) with angioid streaks were evaluated. The first pacient showed choroidal neovascularization and subretinal fibrosis, which was treated with intravitreal ranibizumab. The second case had macular atrophy in one eye in association with subretinal fibrosis in the contralateral eye. Results A single dose of intravitreal ranibizumab improved the structural features of exudative maculopathy. Functional improvement (visual acuity) was less important because of subretinal fibrosis. Atrophic maculopathy was not susceptible to treatment. Conclusion Angioid streaks diagnosis is usually late. It must be suspect in middle aged pacients with choroidal neovascularization and their visual prognosis depends on early treatment. Macular atrophy associated to angioid streaks is very uncommon.