INCIDENCE OF ADENOMYOSIS AND THEIR ASSOCIATIONS WITH OTHER UTERINE WALL PATHOLOGIES IN HYSTERECTOMY SPECIMENS

BACKGROUND: Adenomyosis is a gynaecological condition in which there occurs an ectopicendometrial tissue in myometrial layer of uterine wall. Adenomyosis is one of the most common causesof abnormal uterine bleeding.OBJECTIVE: To determine the incidence of adenomyosis and their association with other uterinepathologies in hysterectomy specimens in northern district of Khyber pukhthunkhwa.MATERIALS AND METHODS: This descriptive study was conducted in Gynecology department andPathology department of Saidu Medical College / Saidu teaching hospital Swat. The study period wasfrom June 2013 to June 2016. A total of 250 hysterectomies were included in the study. The inclusioncriteria was only hysterectomies specimens of any age, whereas exclusion criteria were autolysedspecimen. A minimum of two sections and a maximum of six sections were taken from the uterine wall.Sections 5 micron thick were stained with H&E and reported by histopathologists. The data wasanalysed in Statistical Package for Social Sciences (SPSS) version 16 for frequencies with percentagesand mean with standard deviation.RESULTS: A total of 250 hysterectomies were included in this study with mean age of 37.5±8.47 yearsand age range was from 25 to 65 years. The incidence of adenomyosis was 34.8% amongst 250hysterectomies specimens and was the second common lesion where as leiomyoma was the firstcommon lesion. The most common age group in adenomyosis was between 35-45 years 43(49.42%)cases followed by 25-35 years 32(36.78%) cases etc. Adenomyosis was present in 84(95.40%) caseswith endometrial wall thickness of more than 2.5 millimeter.CONCLUSION: Adenomyosis was the second commonest lesion in hysterectomy specimen and wassignificantly associated with other uterine pathologies.KEY WORDS: Hysterectomy, Adenomyosis, Uterine wall thickness.