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Figure S4 from Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma
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<p>Correlation between mRANO-defined PFS and OS excluding patients with PFS > 120 days. (top) Correlation between radiographic PFS using the mRANO criteria applied to local measurements and OS for patients who died. (bottom) Correlation between radiographic PFS using the mRANO criteria applied to IRF-determined measurements and OS for patients who died. Open circles = patients who were censored (not used in correlation analysis, only for visualization purposes).</p>
American Association for Cancer Research (AACR)
Benjamin M. Ellingson
John Sampson
Achal Singh Achrol
Manish K. Aghi
Krystof Bankiewicz
Chencai Wang
Martin Bexon
Steven Brem
Andrew Brenner
Sajeel Chowdhary
John R. Floyd
Seunggu Han
Santosh Kesari
Dina Randazzo
Michael A. Vogelbaum
Frank Vrionis
Miroslaw Zabek
Nicholas Butowski
Melissa Coello
Nina Merchant
Fahar Merchant
Title: Figure S4 from Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma
Description:
<p>Correlation between mRANO-defined PFS and OS excluding patients with PFS > 120 days.
(top) Correlation between radiographic PFS using the mRANO criteria applied to local measurements and OS for patients who died.
(bottom) Correlation between radiographic PFS using the mRANO criteria applied to IRF-determined measurements and OS for patients who died.
Open circles = patients who were censored (not used in correlation analysis, only for visualization purposes).
</p>.
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Data from Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma
Data from Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma
<div>AbstractPurpose:<p>The current study compared the standard response assessment in neuro-oncology (RANO), immunotherapy RANO (iRANO), and modified RANO (mRANO) crit...
Figure S5 from Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma
Figure S5 from Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma
<p>Correlation between duration of clinical benefit (DOCB) and overall survival (OS) for the standard RANO, iRANO, and mRANO criteria. (A) Correlation between radiographic DO...
Figure S5 from Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma
Figure S5 from Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma
<p>Correlation between duration of clinical benefit (DOCB) and overall survival (OS) for the standard RANO, iRANO, and mRANO criteria. (A) Correlation between radiographic DO...
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Figure S3 from Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma
Figure S3 from Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma
<p>Additional example of patient experiencing immune-related pseudoprogression (PsP)</p>...
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