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Recent Advances in the Synthesis of Coumarin and Its Derivatives by Using Aryl Propiolates
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Abstract
Coumarins (2
H
‐1‐benzopyran‐2‐one) are a class of natural products extracted from plant with a broad range of biological activities like antitubercular, anti‐inflammatory, anticancer, anticonvulsant, neuroprotective, antiviral, antifungal, antibacterial, antihyperglycemic, anticoagulant, antihypertensive, antiadipogenic, and antioxidant, effects. Therefore, the synthesis of coumarin and its derivatives has become amongst the most attractive compounds over the last two decades in the growth of improved synthetic methods to form various coumarins derivatives. Amongst the reported methods for the construction of coumarins, the pendant arylpropiolate scaffolds served as a highly appealing precursor for coumarins in a single step. This review article describes recent updates on the construction of coumarins using arylpropiolate as substrates.
Title: Recent Advances in the Synthesis of Coumarin and Its Derivatives by Using Aryl Propiolates
Description:
Abstract
Coumarins (2
H
‐1‐benzopyran‐2‐one) are a class of natural products extracted from plant with a broad range of biological activities like antitubercular, anti‐inflammatory, anticancer, anticonvulsant, neuroprotective, antiviral, antifungal, antibacterial, antihyperglycemic, anticoagulant, antihypertensive, antiadipogenic, and antioxidant, effects.
Therefore, the synthesis of coumarin and its derivatives has become amongst the most attractive compounds over the last two decades in the growth of improved synthetic methods to form various coumarins derivatives.
Amongst the reported methods for the construction of coumarins, the pendant arylpropiolate scaffolds served as a highly appealing precursor for coumarins in a single step.
This review article describes recent updates on the construction of coumarins using arylpropiolate as substrates.
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