Optimizing Contemporary Orthodontic Treatment using the 2×4 Appliance: Review of Techniques and Outcomes

With the new emphasis on timely management of malocclusions to avert the consequences of untreated malocclusion, interceptive orthodontics has both simplified, and eliminated the need for future intervention. The 2×4 appliance is a kind of fixed orthodontic appliance that is specifically indicated in the period of mixed dentition to address transitional dental problems such as anterior crossbites, open bites, deep bites, crowding, and rotations. This narrative review describes the uses, advantages, disadvantages, and the modifications of the 2×4 appliance. Thedatabases of PubMed, Scopus, Cochrane Library, Google Scholar, and grey literature databases were searched for clinical trials, observational studies, and case reports/series looking in English using multiple searching terms. Out of 64 articles, 35 were relevant articles that screened, appraised and summarized in this review. The 2×4 appliance is indicated for mixed dentition patients who present with either mild or moderate malocclusions, especially when removable appliance compliance is a significant concern. Owing to their advantages, the usage of such appliance is recommended by orthodontists and pedodontists