Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
HUGIn: Hi-C Unifying Genomic Interrogator
View through CrossRef
Abstract
Motivation
High throughput chromatin conformation capture (3C) technologies, such as Hi-C and ChlA-PET, have the potential to elucidate the functional roles of non-coding variants. However, most of published genome-wide unbiased chromatin organization studies have used cultured cell lines, limiting their generalizability.
Results
We developed a web browser, HUGIn, to visualize Hi-C data generated from 21 human primary tissues and cell liens. HUGIn enables assessment of chromatin contacts both constitutive across and specific to tissue(s) and/or cell line(s) at any genomic loci, including GWAS SNPs, eQTLs and cis-regulatory elements, facilitating the understanding of both GWAS and eQTLs results and functional genomics data.
Availability
HUGIn is available at
http://yunliweb.its.unc.edu/HUGIn
.
Contact
yunli@med.unc.edu
and
hum@ccf.org
Supplementary information:
Title: HUGIn: Hi-C Unifying Genomic Interrogator
Description:
Abstract
Motivation
High throughput chromatin conformation capture (3C) technologies, such as Hi-C and ChlA-PET, have the potential to elucidate the functional roles of non-coding variants.
However, most of published genome-wide unbiased chromatin organization studies have used cultured cell lines, limiting their generalizability.
Results
We developed a web browser, HUGIn, to visualize Hi-C data generated from 21 human primary tissues and cell liens.
HUGIn enables assessment of chromatin contacts both constitutive across and specific to tissue(s) and/or cell line(s) at any genomic loci, including GWAS SNPs, eQTLs and cis-regulatory elements, facilitating the understanding of both GWAS and eQTLs results and functional genomics data.
Availability
HUGIn is available at
http://yunliweb.
its.
unc.
edu/HUGIn
.
Contact
yunli@med.
unc.
edu
and
hum@ccf.
org
Supplementary information:.
Related Results
HUGIN 3000 AUV for Deepwater Surveying
HUGIN 3000 AUV for Deepwater Surveying
Abstract
The existing HUGIN vehicles have been used for seabed surveying in water depths down to 500 meters, both in tests and commercial work. This has provided ...
Fracture formation due to differential compaction under glacial load: a poro-elastoplastic simulation of the Hugin Fracture
Fracture formation due to differential compaction under glacial load: a poro-elastoplastic simulation of the Hugin Fracture
AbstractThe Hugin Fracture, discovered in 2011, is an approximately 3.5 km long seafloor fracture in the North Sea. This fracture was unexpected and, due to the geology in the Nort...
Hugin-AstA circuitry is a novel central energy sensor that directly regulates sweet sensation in Drosophila and mouse
Hugin-AstA circuitry is a novel central energy sensor that directly regulates sweet sensation in Drosophila and mouse
Taste sensation plays a crucial role in shaping feeding behavior and is intricately influenced by internal states like hunger or satiety. Despite the identification of numerous neu...
RAPD and ISSR Methods Used for Fingerprinting Selected, Closely Related Cultivars of Aronia melanocarpa
RAPD and ISSR Methods Used for Fingerprinting Selected, Closely Related Cultivars of Aronia melanocarpa
RAPD (Random Amplified Polymorphic DNA) and ISSR (Inter Simple Sequence Repeats) markers were used to analyse the genetic diversity between six genotypes of Aronia melanocarpa (H...
Neuropeptidergic circuit modulation of developmental sleep in Drosophila
Neuropeptidergic circuit modulation of developmental sleep in Drosophila
Abstract
Sleep-wakefulness regulation dynamically evolves along development in flies, fish, and humans. While the mechanisms regulating sleep in adults are relative...
Neuropeptidergic circuit modulation of developmental sleep in Drosophila
Neuropeptidergic circuit modulation of developmental sleep in Drosophila
Sleep-wakefulness regulation dynamically evolves along development in a wide range of organisms. While the mechanism regulating sleep in adults are relatively well understood, litt...
Karakteristik Reservoir Hidrokarbon Silisiklastik: Studi Kasus Formasi Hugin, North Sea
Karakteristik Reservoir Hidrokarbon Silisiklastik: Studi Kasus Formasi Hugin, North Sea
Studi berlokasi di Lapangan Volve, North Sea, khususnya pada Formasi Hugin yang merupakan salah satu formasi dengan litologi batupasir dari Vestland Group yang memiliki prospek hid...
HUGIN 1000 Arctic Class AUV
HUGIN 1000 Arctic Class AUV
Abstract
The HUGIN 1000 Arctic Class AUV system addresses new challenges of the Arctic environment. With its high Area Coverage Rate (ACR), made possible by use o...