POLYHYDRAMNIOS

Background: Polyhydramnios is a condition characterized by excessiveamniotic fluid around the baby. The most widespread causes of severe Polyhydramnios are fetalanomalies often linked with a primary genetic anomaly. However, gestational diabetes, multiplepregnancies and idiopathic factors are commonly related with milder cases. So, we designedthis study to see the association of polyhydramnios and perinatal outcome. Objectives: Tocompare the Perinatal outcomes in patients with explained and unexplained Polyhydramnios.Study Design: Cohort study. Setting: Obstetrics & Gynaecology Department and Diabetesclinic of Postgraduate Medical Institute, Lahore General Hospital. Period: 6 months From Jan2014 to June 2014. Material & Methods: 300 females were included through Non probabilitypurposive sampling. Informed consent and Demographic history was recorded. The patientswere divided into two groups. Those having congenital anomalies and diabetes mellitusdetermined by ultrasonography and laboratory investigations were included in Group ‘I’ andpatients with no detectable cause of polyhydramnios were included in Group ‘II’. All the data wasrecorded in well-defined proforma. Data was entered and analyzed through SPSS 20. Relativerisk was calculated to see any association between perinatal outcomes in both study groups.RR > 1 was considered as statistically significant. Results: The mean age of the patients wasnoted as 29.37±5.37 years. The mean gestational age was noted as 34.82±2.09 weeks. In thisstudy, Macrosomia was observed in 60 (20%) cases whereas Malpresentation was observedin 51 (17%) cases. Malpresentation was observed in 51 patients out of which 14 (27.5%) werefrom explained Polyhydramnios and 37 (72.5%) were from unexplained Polyhydramnios group.Statistically there is significant difference between the study groups i.e. RR=3.181. Macrosomiawas observed in 60 patients out of which 18 (30%) were from explained Polyhydramnios groupand 42 (70%) were from unexplained Polyhydramnios group. Statistically there is significantdifference between the study groups i.e. RR=2.852. Conclusion: It was concluded throughresults of this study that unexplained Polyhydramnios has more risk of developing adverseperinatal outcome.