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Pattern of Presentation and Management of Ectopic Pregnancy in Tertiary Care Hospital

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Background: Ectopic pregnancy remains a significant obstetric emergency contributing to maternal morbidity and mortality, particularly in resource-limited settings where delayed diagnosis and complications frequently occur. Objective: To analyze clinical presentation patterns, risk factors, diagnostic parameters, and management outcomes of ectopic pregnancy among patients admitted to a tertiary care hospital. Methods: A hospital-based observational study is conducted in the Department of Gynecology and Obstetrics, Rajshahi Medical College Hospital, from January–December 2025. Ninety-eight confirmed ectopic pregnancy cases are included using purposive sampling. Data include demographic variables, reproductive history, risk factors, clinical presentation, β-hCG levels, ultrasound findings, management approach, complications, and hospital stay. Statistical analysis uses descriptive statistics, mean ± standard deviation, chi-square testing, and significance at p<0.05. Results: Among 98 patients, mean age is 27.9 ± 5.4 years. The largest group (46.9%) falls within 26–30 years. Abdominal pain occurs in 91.8%, amenorrhea in 86.7%, and vaginal bleeding in 62.2%. Previous pelvic inflammatory disease is identified in 29.6%, prior abortion in 24.5%, infertility treatment in 10.2%, and previous ectopic pregnancy in 7.1%. Mean serum β-hCG level at admission is 3215 ± 1480 mIU/mL. Ultrasound detects adnexal mass in 88.8% and hemoperitoneum in 41.8%. Ruptured ectopic pregnancy accounts for 57.1%. Surgical management is performed in 72.4%, while 19.4% receive methotrexate therapy and 8.2% are managed expectantly. Mean hospital stay is 4.6 ± 1.8 days. Significant associations are observed between delayed presentation and rupture (χ²=9.62, p=0.002) and between high β-hCG levels (>3000 mIU/mL) and surgical management (p=0.01). Conclusion: Ectopic pregnancy frequently presents with abdominal pain and amenorrhea. Early diagnosis using ultrasound and β-hCG assessment significantly improves management outcomes and reduces complications in tertiary healthcare settings.
Title: Pattern of Presentation and Management of Ectopic Pregnancy in Tertiary Care Hospital
Description:
Background: Ectopic pregnancy remains a significant obstetric emergency contributing to maternal morbidity and mortality, particularly in resource-limited settings where delayed diagnosis and complications frequently occur.
Objective: To analyze clinical presentation patterns, risk factors, diagnostic parameters, and management outcomes of ectopic pregnancy among patients admitted to a tertiary care hospital.
Methods: A hospital-based observational study is conducted in the Department of Gynecology and Obstetrics, Rajshahi Medical College Hospital, from January–December 2025.
Ninety-eight confirmed ectopic pregnancy cases are included using purposive sampling.
Data include demographic variables, reproductive history, risk factors, clinical presentation, β-hCG levels, ultrasound findings, management approach, complications, and hospital stay.
Statistical analysis uses descriptive statistics, mean ± standard deviation, chi-square testing, and significance at p<0.
05.
Results: Among 98 patients, mean age is 27.
9 ± 5.
4 years.
The largest group (46.
9%) falls within 26–30 years.
Abdominal pain occurs in 91.
8%, amenorrhea in 86.
7%, and vaginal bleeding in 62.
2%.
Previous pelvic inflammatory disease is identified in 29.
6%, prior abortion in 24.
5%, infertility treatment in 10.
2%, and previous ectopic pregnancy in 7.
1%.
Mean serum β-hCG level at admission is 3215 ± 1480 mIU/mL.
Ultrasound detects adnexal mass in 88.
8% and hemoperitoneum in 41.
8%.
Ruptured ectopic pregnancy accounts for 57.
1%.
Surgical management is performed in 72.
4%, while 19.
4% receive methotrexate therapy and 8.
2% are managed expectantly.
Mean hospital stay is 4.
6 ± 1.
8 days.
Significant associations are observed between delayed presentation and rupture (χ²=9.
62, p=0.
002) and between high β-hCG levels (>3000 mIU/mL) and surgical management (p=0.
01).
Conclusion: Ectopic pregnancy frequently presents with abdominal pain and amenorrhea.
Early diagnosis using ultrasound and β-hCG assessment significantly improves management outcomes and reduces complications in tertiary healthcare settings.

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