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Study on the Interaction between Silibinin and Neuraminidase
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Background:
Neuraminidase is a pathogenic protein of the avian influenza virus. Previous studies
have shown that silibinin has the potential to inhibit neuraminidase activity.
Objective:
This study aims to explore the interaction between silibinin and neuraminidase and the effect of
silibinin on the structure and activity of neuraminidase.
Methods:
In this study, two-dimensional fluorescence spectrum, three-dimensional fluorescence spectrometry,
Uv-vis spectroscopy, and Circular dichroism analysis were used.
Results:
Silibinin alters the secondary structure of neuraminidase and inhibits the activity of neuraminidase.
Conclusion:
Silibinin can interact with neuraminidase and inhibit its activity.
Bentham Science Publishers Ltd.
Title: Study on the Interaction between Silibinin and Neuraminidase
Description:
Background:
Neuraminidase is a pathogenic protein of the avian influenza virus.
Previous studies
have shown that silibinin has the potential to inhibit neuraminidase activity.
Objective:
This study aims to explore the interaction between silibinin and neuraminidase and the effect of
silibinin on the structure and activity of neuraminidase.
Methods:
In this study, two-dimensional fluorescence spectrum, three-dimensional fluorescence spectrometry,
Uv-vis spectroscopy, and Circular dichroism analysis were used.
Results:
Silibinin alters the secondary structure of neuraminidase and inhibits the activity of neuraminidase.
Conclusion:
Silibinin can interact with neuraminidase and inhibit its activity.
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