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Management of Aromatase Inhibitor–Induced Arthralgia
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Aromatase inhibitors (AIS) are commonly used as adjuvant treatment in postmenopausal women with hormone receptor–positive early breast cancer. With both steroidal and nonsteroidal AIS, AI-induced arthralgia is frequently observed. The mechanism of AI-induced arthralgia remains unknown, and the data available from clinical trails using AIS are limited. We review the pertinent information from a clinical perspective, including an algorithm to treat AI-induced arthralgia.
Title: Management of Aromatase Inhibitor–Induced Arthralgia
Description:
Aromatase inhibitors (AIS) are commonly used as adjuvant treatment in postmenopausal women with hormone receptor–positive early breast cancer.
With both steroidal and nonsteroidal AIS, AI-induced arthralgia is frequently observed.
The mechanism of AI-induced arthralgia remains unknown, and the data available from clinical trails using AIS are limited.
We review the pertinent information from a clinical perspective, including an algorithm to treat AI-induced arthralgia.
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