Clinico-pathological Alterations of Pyometra in Cat

Background: Pyometra is an infectious condition characterized by a pus-filled uterus, which basically developed due to hormonal, anatomical and physiological changes and the inside environment of the queen uterus help to grow the opportunistic pathogen. The aim of the present study was made to assess the haemato-biochemical changes of pyometra in infected queens. Methods: The study was carried out in 12 clinical cases of cat with a history of lethargy, depression, inappetence, polydipsia, occasional vomition and vaginal discharge, presented for treatment at Teaching Veterinary Clinical Complex, College of Veterinary Sciences and A.H., Central Agricultural University, Aizawl, Mizoram. The presumptive clinical diagnosis of pyometra was made based on history, clinical signs and imaging techniques. The involvement of the pathogen was further confirmed by microbial examination of the pus-filled uterus after the ovariohysterectomy. Result: The study revealed alterations in the total erythrocyte count, haemoglobin and packed cell volume in pyometra cases. The leucogram revealed leucocytosis, neutrophilia and lymphopenia. Biochemical analysis revealed hyperprotenemia, increased liver enzymes and BUN and creatinine. The major pathogens involved in pyometra infected queens are Escherichia coli, Staphylococcus, Streptococcus, Pseudomonas, Proteus and Pasteurella. The analysis of various parameters indicated that haemato-biochemical analysis may be good prognostic markers for feline pyometra.