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In-Vivo Functional and Structural Retinal Imaging Using Multiwavelength Photoacoustic Remote Sensing Microscopy and Optical Coherence Tomography
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Abstract
A multiwavelength photoacoustic remote sensing (PARS) microscope is combined with swept-source optical coherence tomography and applied to in-vivo, non-contact retinal imaging. Building on the proven strength of multiwavelength PARS imaging, the system is applied for estimating retinal oxygen saturation in the rat eye. The capability of the technology is demonstrated by imaging both microanatomy and the microvasculature of the retina in-vivo. To our knowledge, this is the first time a non-contact photoacoustic imaging technique is employed for in-vivo oxygen saturation measurement in the retina.
Research Square Platform LLC
Title: In-Vivo Functional and Structural Retinal Imaging Using Multiwavelength Photoacoustic Remote Sensing Microscopy and Optical Coherence Tomography
Description:
Abstract
A multiwavelength photoacoustic remote sensing (PARS) microscope is combined with swept-source optical coherence tomography and applied to in-vivo, non-contact retinal imaging.
Building on the proven strength of multiwavelength PARS imaging, the system is applied for estimating retinal oxygen saturation in the rat eye.
The capability of the technology is demonstrated by imaging both microanatomy and the microvasculature of the retina in-vivo.
To our knowledge, this is the first time a non-contact photoacoustic imaging technique is employed for in-vivo oxygen saturation measurement in the retina.
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