A Two-year Cross-sectional Prospective Study for Assessment of Endometrial Thickness and Volume using Three-dimensional Transvaginal Ultrasound among in vitro Fertilization Patients of Royan Institute in Iran

ABSTRACT Introduction To evaluate the role of endometrial thickness and volume using three-dimensional transvaginal ultrasound (3-D TVUS) in order to predict pregnancy outcome in assisted reproductive technology (ART) cycle on the day of human chorionic gonadotropin (hCG) administration. Materials and methods In this prospective study, the long protocol of controlled ovarian hyperstimulation was prescribed for women. Endometrial thickness and volume were measured using the 3-D TVUS, for 166 women undergoing ART cycle, on the day of hCG administration at Royan Institute, Tehran, Iran, between 2009 and 2011. All patients were divided into three groups. Regarding endometrial thickness, there are three groups as follows: Group I: . 7 mm, group II: 7.14 mm, and group III: > 14 mm; all patients were also divided into three groups according to endometrial volume calculated as follows: Group IV: < 2 cc, group V: 2.4.5 cc, group VI: > 4.5 cc. Pregnancy rate (PR) was compared between all groups. Results A total of 166 patients were analyzed. Overall PR was 39.8% after in vitro fertilization (IVF). Participant's age ranged from 20 to 38 years old with the mean age of 29.9 ± 4.23. No significant cut-off value was found for endometrial thickness and volume. Conclusion Endometrial thickness and volume on the day of hCG are significant in limited value and in a clinical setting for predicting implantation in ART cycle. How to cite this article Ahmadi F, Akhbari F, Irani SH, Shiva M, Maghari A. A Two-year Cross-sectional Prospective Study for Assessment of Endometrial Thickness and Volume using Threedimensional Transvaginal Ultrasound among in vitro Fertilization Patients of Royan Institute in Iran. Donald School J Ultrasound Obstet Gynecol 2016;10(4):398-402.