Antioxidant properties of African mahogany (Khaya senegalensis (Desr.) A. Juss.) seed oil

This study investigated the phytochemical constituents and antioxidant properties of Khaya senegalensis seed oil. Using standard analytical methods, the presence of saponins, steroids, terpenoids, cardiac glycosides, alkaloids, and proteins was confirmed, while flavonoids, tannins, reducing sugars, and anthraquinones were absent. Quantitative analysis showed high contents of flavonoids (106.38 ± 0.65), proanthocyanidins (103.74 ± 7.49), tannins (21.68 ± 0.81), and phenolics (17.60 ± 0.34). In vitro antioxidant assays demonstrated that K. senegalensis seed oil exhibited significant ferric reducing antioxidant power and strong nitric oxide scavenging activity, particularly at lower concentrations. However, its scavenging potential against DPPH radicals and lipid peroxidation was relatively lower compared to ascorbic acid. These findings underscore the potential of K. senegalensis seed oil as a valuable source of natural antioxidants, highlighting its possible application in dietary supplements and medicinal formulations. Rich in bioactive compounds, such as steroids, cardiac glycosides, and proteins, the seed oil holds promise for combating oxidative stress-related health issues. Further research exploring its precise antioxidant mechanisms and therapeutic efficacy is recommended, reinforcing its potential as a sustainable resource for enhancing human health and wel -being. is recommended, reinforcing its potential as a sustainable resource for enhancing human health and well-being.