Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Effect of Hypovolemic Shock on the Generalized Shwartzman Reaction
View through CrossRef
The generalized Shwartzman reaction was produced in rabbits by two intravenous injections of endotoxin given 20–22 h apart. Prior to the second injection of endotoxin, the animals were made hypovolemic by removal of 40% blood volume or reduction of the systolic pressure to 70% of normal, whichever came first. This blood removal produced a persistent hypotensive episode. 8/9 rabbits made hypotensive in this manner had evidence of glomerular capillary thrombi compared to 8/8 in a group that did not have blood removed. It is concluded that hypovolemic shock of this magnitude does not prevent the generalized Shwartzman reaction.
Title: Effect of Hypovolemic Shock on the Generalized Shwartzman Reaction
Description:
The generalized Shwartzman reaction was produced in rabbits by two intravenous injections of endotoxin given 20–22 h apart.
Prior to the second injection of endotoxin, the animals were made hypovolemic by removal of 40% blood volume or reduction of the systolic pressure to 70% of normal, whichever came first.
This blood removal produced a persistent hypotensive episode.
8/9 rabbits made hypotensive in this manner had evidence of glomerular capillary thrombi compared to 8/8 in a group that did not have blood removed.
It is concluded that hypovolemic shock of this magnitude does not prevent the generalized Shwartzman reaction.
Related Results
Whatever happened to the Shwartzman phenomenon?
Whatever happened to the Shwartzman phenomenon?
Ninety years ago, Gregory Shwartzman first reported an unusual discovery following the intradermal injection of sterile culture filtrates from principally Gram-negative strains fro...
Neutralization of the Shwartzman Reactions by Polymyxin B
Neutralization of the Shwartzman Reactions by Polymyxin B
Summary
Polymyxin B prevented the localized Shwartzman reaction in rabbits when admixed with the intravenous (i.v.) provocative dose of endotoxin but enhanced the re...
Generation and modulation of shock waves in two-dimensional polariton condensates
Generation and modulation of shock waves in two-dimensional polariton condensates
Due to the ability of exciton-polariton condensates formed in semiconductor microcavities to be achieved at room temperature and their characteristics such as non-equilibrium and s...
The pharmacokinetics of intraosseous atropine in hypovolemic swine
The pharmacokinetics of intraosseous atropine in hypovolemic swine
Objective: Compare the pharmacokinetics of atropine administered via the intravenous (IV), intramuscular (IM), and intraosseous (IO) routes in a normovolemic and hypovolemic swine ...
Refractory Shock. Casuistics
Refractory Shock. Casuistics
Shock Syndrome is an acute progressive circulatory insufficiency where the Heart is unable to circulate the blood in time unit, for supplying with O2 to the cells and to take out f...
Propagation of a curved weak shock
Propagation of a curved weak shock
Propagation of a curved shock is governed by a system of shock ray equations which
is coupled to an infinite system of transport equations along these rays. For a two-dimensional ...
Reviving the Critically Ill: Exploring Effective Fluid Resuscitation Approaches for Diverse Hypovolemic Shock Cases – A Systematic Review and Meta-Analysis
Reviving the Critically Ill: Exploring Effective Fluid Resuscitation Approaches for Diverse Hypovolemic Shock Cases – A Systematic Review and Meta-Analysis
Abstract
Background
Hypovolemic shock is a potentially life-threatening condition, which when left untreated, may result in multiple organ failure. This condition is chara...
Blast Wave Mitigation Through Confined Volume and Porous Material
Blast Wave Mitigation Through Confined Volume and Porous Material
Abstract
Over a period of time, the impact of shock waves on human bodies and structures has been studied. To understand the shock wave mitigation over confined volume and ...