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Aqueous Extract of Dillenia indica Fruit (AEDI): A Sustainable Biocatalyst for the Synthesis of Pharmacologically Important Bis(indolyl)methanes

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Abstract A highly effective green technique for the synthesis of bis(indolyl) methanes mediated by ‘Aqueous Extract of Dillenia indica’ (AEDI) is developed. The reaction involves a simple procedure at a moderate temperature of below 60 °C in air within a short reaction time of 30–60 minutes under conditions free from external promoters, acids, ligands/organic media using our natural water–extracted catalyst, affording moderate to high yield. This protocol offers a mild, effective, and highly economical alternative to the existing protocols and promotes a more environmentally friendly alternative for the protic and Lewis acids catalysts that are already in use.
Title: Aqueous Extract of Dillenia indica Fruit (AEDI): A Sustainable Biocatalyst for the Synthesis of Pharmacologically Important Bis(indolyl)methanes
Description:
Abstract A highly effective green technique for the synthesis of bis(indolyl) methanes mediated by ‘Aqueous Extract of Dillenia indica’ (AEDI) is developed.
The reaction involves a simple procedure at a moderate temperature of below 60 °C in air within a short reaction time of 30–60 minutes under conditions free from external promoters, acids, ligands/organic media using our natural water–extracted catalyst, affording moderate to high yield.
This protocol offers a mild, effective, and highly economical alternative to the existing protocols and promotes a more environmentally friendly alternative for the protic and Lewis acids catalysts that are already in use.

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