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Efficacy of single dose albendazole and praziquantel drugs among helminth-infected school children at Rural Bahir Dar, northwest Ethiopia
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The resistance of anthelminthic drugs makes helminth control difficult. The aim of our study was to assess the efficacy of single dose albendazole and praziquantel drugs among helminth-infected children. A cross-sectional study was conducted from April to June, 2017. Stool examination was done by the Formol-Ether concentration technique. Students infected with geohelminths and s chistosoma mansoni were treated with a single dose of albendazole and praziquantel, respectively. Post-treatment stool examination was performed after two weeks. The magnitude of parasite infection, percentage of egg count reduction and cure rate following treatment were calculated using descriptive statistics. A total of 409 Sebatamet primary school students were included. The total prevalence of intestinal parasitosis was 58%. The cure rate of albendazole against hookworm was only 76.8%. Praziquantel had a 91.4% cure rate against Schistosoma mansoni. Therefore, periodic evaluation of the efficacy of anthelminthic drugs is required.
Title: Efficacy of single dose albendazole and praziquantel drugs among helminth-infected school children at Rural Bahir Dar, northwest Ethiopia
Description:
The resistance of anthelminthic drugs makes helminth control difficult.
The aim of our study was to assess the efficacy of single dose albendazole and praziquantel drugs among helminth-infected children.
A cross-sectional study was conducted from April to June, 2017.
Stool examination was done by the Formol-Ether concentration technique.
Students infected with geohelminths and s chistosoma mansoni were treated with a single dose of albendazole and praziquantel, respectively.
Post-treatment stool examination was performed after two weeks.
The magnitude of parasite infection, percentage of egg count reduction and cure rate following treatment were calculated using descriptive statistics.
A total of 409 Sebatamet primary school students were included.
The total prevalence of intestinal parasitosis was 58%.
The cure rate of albendazole against hookworm was only 76.
8%.
Praziquantel had a 91.
4% cure rate against Schistosoma mansoni.
Therefore, periodic evaluation of the efficacy of anthelminthic drugs is required.
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