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CHEMISTRY OF AVERMECTINS AND MILBEMYCINS
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Parasitic diseases are a serious problem for medicine and the agro-industrial complex. The most effective antiparasitic compounds are avermectins, for the discovery of which Satoshi Omura and William Campbell were awarded the 2015 Nobel Prize in Physiology or Medicine. For the first time, the monograph summarizes and analyzes the achievements in the chemistry of avermectins and milbemycins, as well as analyzes the possible directions and patterns of chemical modification of these compounds. In addition, the analysis of data on the relationship «structure-property» allows a more conscious approach to the modification of these compounds in order to increase their biological activity, stability, etc. The monograph is intended for wide range of specialists in the field of chemistry of natural compounds and biologically active substances.
Title: CHEMISTRY OF AVERMECTINS AND MILBEMYCINS
Description:
Parasitic diseases are a serious problem for medicine and the agro-industrial complex.
The most effective antiparasitic compounds are avermectins, for the discovery of which Satoshi Omura and William Campbell were awarded the 2015 Nobel Prize in Physiology or Medicine.
For the first time, the monograph summarizes and analyzes the achievements in the chemistry of avermectins and milbemycins, as well as analyzes the possible directions and patterns of chemical modification of these compounds.
In addition, the analysis of data on the relationship «structure-property» allows a more conscious approach to the modification of these compounds in order to increase their biological activity, stability, etc.
The monograph is intended for wide range of specialists in the field of chemistry of natural compounds and biologically active substances.
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