Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Oligoclonal bands
View through CrossRef
Oligoclonal bands (OCBs) represent the presence of intrathecal immunoglobulin G (IgG) as detected by isoelectric focusing and immunofixation. Cerebrospinal fluid (CSF) analysed alongside a paired serum sample gives five different immunofixation patterns. These are: type 1—the normal physiological state with no intrathecal IgG synthesis; type 2—evidence for intrathecal IgG synthesis, with CSF-restricted OCBs; type 3—evidence for intrathecal IgG synthesis, with CSF-restricted OCBs, but with additional, identical bands in the CSF and serum; type 4—absence of intrathecal IgG synthesis, but with identical OCBs in CSF and serum; and type 5—absence of intrathecal IgG synthesis, with a monoclonal band in CSF and serum. Analysis of these patterns can help to diagnose a range of neurological conditions, including multiple sclerosis. However, it is important to interpret OCB results alongside other CSF tests and their clinical context.
Title: Oligoclonal bands
Description:
Oligoclonal bands (OCBs) represent the presence of intrathecal immunoglobulin G (IgG) as detected by isoelectric focusing and immunofixation.
Cerebrospinal fluid (CSF) analysed alongside a paired serum sample gives five different immunofixation patterns.
These are: type 1—the normal physiological state with no intrathecal IgG synthesis; type 2—evidence for intrathecal IgG synthesis, with CSF-restricted OCBs; type 3—evidence for intrathecal IgG synthesis, with CSF-restricted OCBs, but with additional, identical bands in the CSF and serum; type 4—absence of intrathecal IgG synthesis, but with identical OCBs in CSF and serum; and type 5—absence of intrathecal IgG synthesis, with a monoclonal band in CSF and serum.
Analysis of these patterns can help to diagnose a range of neurological conditions, including multiple sclerosis.
However, it is important to interpret OCB results alongside other CSF tests and their clinical context.
Related Results
Bands Selection for Multispectral Detection Mode of Lunar Mineralogical Spectrometer of China’s Chang’E-5 and Chang’E-6 Missions
Bands Selection for Multispectral Detection Mode of Lunar Mineralogical Spectrometer of China’s Chang’E-5 and Chang’E-6 Missions
Introduction:  In December 2020, China’s Chang’E-5 (CE-5) mission successfully landed in the northeastern part of Oceanus Procellarum on the Moon and a...
Difference in force decay latex and non-latex elastic band based on duration of elastic use and salivary pH concentration: In vitro study
Difference in force decay latex and non-latex elastic band based on duration of elastic use and salivary pH concentration: In vitro study
OBJECTIVE:
This study aimed to determine the difference in force decay between latex and non-latex elastic bands based on duration of use and salivary pH concentration....
Iconography of Sky Bands, Earth Bands,
Skull & Crossed-Bones Bands in
Classic Maya Art
Iconography of Sky Bands, Earth Bands,
Skull & Crossed-Bones Bands in
Classic Maya Art
This presentation introduces Maya motifs that tend to be in horizontal bands. The most common horizontal band is the Sky Band. The other common horizontal band is the Surface of th...
We Made This Song. The Group Song Writing Processes of Three Adolescent Rock Bands
We Made This Song. The Group Song Writing Processes of Three Adolescent Rock Bands
<p>In garages, practice rooms and classrooms, young people are composing music in rock and pop bands; engaged in working together in the shared enterprise of group music maki...
Oligoclonal bands predict multiple sclerosis after optic neuritis: a literature survey
Oligoclonal bands predict multiple sclerosis after optic neuritis: a literature survey
Background: Multiple sclerosis (MS) is an autoimmune disease resulting in inflammation and demyelination of neurones in the central nervous system (CNS). The first sign of MS is of...
Clinical association of intrathecal and mirrored oligoclonal bands in paediatric neurology
Clinical association of intrathecal and mirrored oligoclonal bands in paediatric neurology
Aim Biomarkers such as autoantibodies, neopterin, and oligoclonal bands (OCBs) are increasingly used for the diagnosis of treatable inflammatory central nervous system (CNS) disor...
MERTIS at Mercury: Mapping the Hermean Surface Mineralogy
MERTIS at Mercury: Mapping the Hermean Surface Mineralogy
Introduction: The MERTIS (MErcury Radiometer and Thermal Infrared Spectrometer) is a mid-infrared imaging instrument onboard the BepiColombo ESA/JAXA mission to Mercury expected to...
Joining a Band1
Joining a Band1
Abstract
Typically, a male band starts when a group of friends (usually at the same school, of the same age, and living in the same locality) gradually evolves into ...