Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
The role of SGOL1 in the prognosis of skin cutaneous melanoma (SKCM)
View through CrossRef
Objective: To analyze the expression of SGOL1 in skin cutaneous melanoma(SKCM) and its relationship with prognosis. Methods: The expression of SGOL1 in SKCM and normal tissues was analyzed by TCGA database. Kaplan-Meier curve was used to analyze the relationship between SGOL1 expression and prognosis of SKCM. Mann-Whitney U test and Kruskal-Wallis test were used to analyze the relationship between SGOL1 and clinicopathological features. Results: SGOL1 was over expressed in SKCM (P <0.05). The overall survival of SGOL1 high expression group was lower than low expression group (P < 0.05). There was no difference in the expression of SGOL1 between gender or age groups, but there were different in the expression of SGOL1 between Clark grades, tumor stages and survival status. Conclusion: High expression of SGOL1 in SKCM may be related with poor prognosis.
Title: The role of SGOL1 in the prognosis of skin cutaneous melanoma (SKCM)
Description:
Objective: To analyze the expression of SGOL1 in skin cutaneous melanoma(SKCM) and its relationship with prognosis.
Methods: The expression of SGOL1 in SKCM and normal tissues was analyzed by TCGA database.
Kaplan-Meier curve was used to analyze the relationship between SGOL1 expression and prognosis of SKCM.
Mann-Whitney U test and Kruskal-Wallis test were used to analyze the relationship between SGOL1 and clinicopathological features.
Results: SGOL1 was over expressed in SKCM (P <0.
05).
The overall survival of SGOL1 high expression group was lower than low expression group (P < 0.
05).
There was no difference in the expression of SGOL1 between gender or age groups, but there were different in the expression of SGOL1 between Clark grades, tumor stages and survival status.
Conclusion: High expression of SGOL1 in SKCM may be related with poor prognosis.
Related Results
Observed Survival Interval: A Supplement to TCGA Pan-Cancer Clinical Data Resource
Observed Survival Interval: A Supplement to TCGA Pan-Cancer Clinical Data Resource
To drive high-quality omics translational research using The Cancer Genome Atlas (TCGA) data, a TCGA Pan-Cancer Clinical Data Resource was proposed. However, there is an out-of-ste...
Identification of Biomarkers with Therapeutic And prognostic Value in Skin Cutaneous Melanoma
Identification of Biomarkers with Therapeutic And prognostic Value in Skin Cutaneous Melanoma
Abstract
Background
The morbidity and mortality of skin cutaneous melanoma (SKCM), the most deadly type of skin cancer, are on the rise worldwide. Through in-depth study o...
The Therapeutic and Prognostic Value of Chemokine Receptors (CXCRs) in Skin Cutaneous Melanoma (SKCM) Progression
The Therapeutic and Prognostic Value of Chemokine Receptors (CXCRs) in Skin Cutaneous Melanoma (SKCM) Progression
Abstract
Introduction:Skin cutaneous melanoma (SKCM) is an aggressive cancer and associates with CXC chemokine receptors (CXCRs). CXCRs is a group of membrane protein invol...
Cometary Physics Laboratory: spectrophotometric experiments
Cometary Physics Laboratory: spectrophotometric experiments
<p><strong><span dir="ltr" role="presentation">1. Introduction</span></strong&...
Abstract LB163: Germline pathogenic variants in melanoma patients
Abstract LB163: Germline pathogenic variants in melanoma patients
Abstract
Background: The etiology of melanoma has generally been thought to be exposure to UV radiation (sun and sun tanning lamps). However, the percent of melanoma...
Precursors of skin melanoma (melanoma-sensitive nevi)
Precursors of skin melanoma (melanoma-sensitive nevi)
Interest in melanoma precursors, or melanoma-sensitive skin nevi, has not lost its relevance for many years due to the steady increase of skin melanoma morbidity in recent decades ...
Identification of Prognostic Signature and Immune Infiltration in the Skin Cutaneous Melanoma Microenvironment
Identification of Prognostic Signature and Immune Infiltration in the Skin Cutaneous Melanoma Microenvironment
Abstract
Skin cutaneous melanoma (SKCM), characterized by high immunogenicity, has an increasing incidence in recent years. The development of immunotherapy recently offere...
CURRENT APPROACH ON CUTANEOUS MELANOMA DIAGNOSTICS
CURRENT APPROACH ON CUTANEOUS MELANOMA DIAGNOSTICS
Melanoma is on the first place in mortality among all skin tumors. Over the past 50 years, there has been a steady increase in the incidence of cutaneous melanoma compared to other...