Value of cerebrovascular hemodynamics and thromboelasto¬gram-related parameters in evaluating the effect of Naomai Jiejing Decoction on the rehabilitation of patients with aneurysmal subarachnoid hemorrhage

Background: To explore the value of cerebrovascular hemodynamic and thromboelastogram-related parameters in evaluating the effect of Naomai Jiejing Decoction (NJD) on the rehabilitation of patients with Aneurysmal subarachnoid hemorrhage (aSAH).Methodology: This article is observational studies.This study compared cerebrovascular hemodynamics, thromboelastogram results, and rehabilitation outcomes between a research group (treated with Naomai Jiejing Decoction) and a control group (not treated with Naomai Jiejing Decoction) of 160 patients with Aneurysmal subarachnoid hemorrhage. Logistic regression analysis explored associations between poor rehabilitation outcomes and hemodynamic/ thromboelastogram-related parameters in the research group.Results: At 12 months after operation, the measured hemodynamics values were lower in research group than those in control group, and the differences were statistically significant (P<0.05). Patients with good rehabilitation outcomes had lower measured hemodynamics values than those with poor rehabilitation outcomes. The results of Logistic regression analysis showed that the high values in hemodynamics and thromboelastogram examinations were risk factors for poor rehabilitation outcomes in research group (P<0.05).Conclusion: Monitoring cerebrovascular hemodynamic and thromboelastogram-related parameters in patients with Aneurysmal subarachnoid hemorrhage receiving Naomai Jiejing Decoction treatment can offer valuable prognostic and therapeutic insights, with improvements correlating to better rehabilitation outcomes, underscoring their significance in assessing intervention effectiveness. Keywords: Aneurysmal subarachnoid hemorrhage; cerebrovascular hemodynamics; thromboelastogram; Naomai Jiejing Decoction; rehabilitation outcome; clinical efficacy.