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Single‐aliquot, non‐bronchoscopic bronchoalveolar lavage in the diagnosis of metastatic mammary tumours in dogs

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ObjectiveTo evaluate the use of bronchoalveolar lavage as an auxiliary tool for the diagnosis of neoplastic lung metastasis from mammary tumours in dogs.MethodsA single‐institution prospective observational study including 20 healthy dogs and 30 with mammary tumours. Thoracic radiography and single‐aliquot, non‐bronchoscopic bronchoalveolar lavage with cytology interpretation was performed in all animals and the results compared between groups.ResultsDogs with mammary gland tumours and radiographic evidence of pulmonary metastasis had significantly higher relative neutrophil counts in bronchoalveolar lavage fluid than dogs with tumours without evidence of metastasis. In only one dog, in which thoracic radiographs were normal, were malignant cells identified in bronchoalveolar lavage fluid.Clinical SignificanceInflammatory bronchoalveolar lavage fluid in dogs with mammary gland tumours may suggest metastatic disease. Bronchoalveolar lavage does not appear to be sensitive for identifying malignant cells.
Title: Single‐aliquot, non‐bronchoscopic bronchoalveolar lavage in the diagnosis of metastatic mammary tumours in dogs
Description:
ObjectiveTo evaluate the use of bronchoalveolar lavage as an auxiliary tool for the diagnosis of neoplastic lung metastasis from mammary tumours in dogs.
MethodsA single‐institution prospective observational study including 20 healthy dogs and 30 with mammary tumours.
Thoracic radiography and single‐aliquot, non‐bronchoscopic bronchoalveolar lavage with cytology interpretation was performed in all animals and the results compared between groups.
ResultsDogs with mammary gland tumours and radiographic evidence of pulmonary metastasis had significantly higher relative neutrophil counts in bronchoalveolar lavage fluid than dogs with tumours without evidence of metastasis.
In only one dog, in which thoracic radiographs were normal, were malignant cells identified in bronchoalveolar lavage fluid.
Clinical SignificanceInflammatory bronchoalveolar lavage fluid in dogs with mammary gland tumours may suggest metastatic disease.
Bronchoalveolar lavage does not appear to be sensitive for identifying malignant cells.

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