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Cutaneous Epithelioid Hemangioendothelioma on the Sole of a Child

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AbstractEpithelioid hemangioendothelioma (EHE) has been considered to be a low‐grade malignant vascular neoplasm, although follow‐up of recent series has demonstrated that EHE involving the skin and soft tissues should be better regarded as a fully malignant vascular tumor since it has more metastatic potential than previously thought. We report a case of an EHE involving the left sole of 6‐year‐old boy, the youngest patient with cutaneous EHE described to date. Immunohistochemical studies demonstrated a lymphatic endothelial line of differentiation for neoplastic cells. Cutaneous EHE is rare in childhood, with only five previously described cases.
Title: Cutaneous Epithelioid Hemangioendothelioma on the Sole of a Child
Description:
AbstractEpithelioid hemangioendothelioma (EHE) has been considered to be a low‐grade malignant vascular neoplasm, although follow‐up of recent series has demonstrated that EHE involving the skin and soft tissues should be better regarded as a fully malignant vascular tumor since it has more metastatic potential than previously thought.
We report a case of an EHE involving the left sole of 6‐year‐old boy, the youngest patient with cutaneous EHE described to date.
Immunohistochemical studies demonstrated a lymphatic endothelial line of differentiation for neoplastic cells.
Cutaneous EHE is rare in childhood, with only five previously described cases.

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