Evaluate the relationship between the incidence of catheter-related bloodstream infection (CRBSI) and phosphorus and parathyroid hormone levels in hemodialysis patients

Abstract Objects This study aimed to determine the relationship between phosphorus and PTH levels with the incidence of catheter related blood stream infection (CRBSI) in hemodialysis (HD) patients. Methods The study was conducted cross-sectionally from April 2021 to September 2022, including individuals who had a permanent catheter for dialysis initiation. Demographic characteristics, physical measurements, and various laboratory tests were recorded, including phosphorus, PTH, and other parameters. The occurrence of CRBSI was also documented. Results In our study involving hemodialysis patients, out of the 100 participants, 19 individuals experienced catheter-related bloodstream infections CRBSI. The average age of patients with CRBSI (62.62±16.52years) was higher than patients without CRBSI (52.33±16.64years), and this difference was statistically significant ( p-value= 0.02). In individuals with (CRBSI), the mean phosphorus level was5.43± 1.47compared to 4.88±1.08, and the mean PTH level was 406.63±263.97 compared to 306.69±389.15. However, this difference was only found to be statistically significant in the case of PTH (p=0.01) Based on the logistic regression test, it was found that age has a significant relationship with CRBSI. With each year of age, the odds of experiencing a catheter-related blood infection increase by 1.1 times. Conclusion: The study concludes that age is a predictive factor for CRBSI, emphasizing the importance of self-care training in this population. Additionally, individuals with high PTH levels should undergo appropriate measures, such as transitioning from a permanent catheter to arteriovenous fistula (AVF), along with proper self-care training, to reduce infectious complications.