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Whole genome sequencing in microbiology
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This chapter addresses how genomics is now one of the most rapidly developing areas in microbiology, mainly due to the rapid progression of whole genome sequencing (WGS) techniques such as Sanger sequencing. As the cost per test has decreased, the more useful WGS has become as a routine diagnostic tool across diagnostic microbiology. These uses include epidemiology, detection of virulence markers, detection of drug resistance, and in vaccine development. In the early 2000s, DNA sequencing changed rapidly with the introduction of ‘non-Sanger’ technologies — so-called next generation sequencing (NGS). As rapid developments in sequencing technologies are occurring every year, they will rapidly change microbiology and enhance its ability to better diagnose and monitor causes of infectious disease throughout the world.
Title: Whole genome sequencing in microbiology
Description:
This chapter addresses how genomics is now one of the most rapidly developing areas in microbiology, mainly due to the rapid progression of whole genome sequencing (WGS) techniques such as Sanger sequencing.
As the cost per test has decreased, the more useful WGS has become as a routine diagnostic tool across diagnostic microbiology.
These uses include epidemiology, detection of virulence markers, detection of drug resistance, and in vaccine development.
In the early 2000s, DNA sequencing changed rapidly with the introduction of ‘non-Sanger’ technologies — so-called next generation sequencing (NGS).
As rapid developments in sequencing technologies are occurring every year, they will rapidly change microbiology and enhance its ability to better diagnose and monitor causes of infectious disease throughout the world.
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