The Role of the Clinical Pharmacist in A Case of Losartan-Induced Faintness and Dysarthria

Background: A common first-line antihypertensive the medication losartan has excellent absorption after being taken orally and undergoes extensive first-pass metabolic processes. Losartan commonly produces feelings of dizziness, headaches, lethargy, nausea, vomiting, impaired vision, and anaemia as side effects. Case summary: We discuss the case of a 59-year-old Yemeni lady who consumed losartan and had fainting and dysarthria. The patient was started on 50 mg daily oral losartan monotherapy for mild hypertension. After 12 days of utilizing the medication, she relocated to the emergency department in Saudi German Hospital in Sana’a city with dizziness, faintness, dysarthria, lightheadedness with generalized weakness. The in-hospital neurological specialist suspected the patient had a transient ischemic attack. On examination, her blood pressure was found to be 150/86, and her heart rate was 72. The patient was treated in the hospital as a stroke patient for five days and discharged with stroke medications. After discharge, on the second day, the patient has the same previous symptoms. Discussion: There was no proof of any other conceivable physiological, infective, naturally occurring, or other pathologic causes of dysarthria, save losartan itself.. A clinical pharmacist discovered adverse drug reaction probability It was "probable" that oral losartan caused the development off fainting and dysarthria in this patient. The drugs for hypertension were changed by the clinical pharmacist to amlodipine 5mg. After 3 days, the patient was stable, and the symptoms resolved. Conclusions: This case report suggests that losartan could induce faintness and dysarthria as side effects