Gastroesophageal Reflux Caused Pharyngitis in Local Population A Comparative Clinical Study

Objective: In gastroesophageal reflux disease gastric contents caused erosive action in esophagus as well as in upper respiratory chamber which is a very common and painful medical complication in our population. Therefore investigation of GERD related risk factors are very important for health awareness. Study Design: A comparative clinical study. Population Sampling: In this study 2000 male and female individuals were selected with gastroesophageal reflux diseases from urban, suburban areas and rural areas. Sample Size: 2000 individuals collectively participated in present study, including 900 from urban areas, 853 from suburban areas, and 1010 from rural areas. Place and Duration: Current study was conducted in Department of Biochemistry Lahore Medical & Dental College Lahore, Indus Medical College Tando Muhammad khan Sindh and Institute of molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore Pakistan from February 2022 to July 2022. Methodology: In current study total 2000 individuals were selected and their interviewee conducted for the completion of questionnaire. The questionnaire was created based on lifestyle factors such as obesity, smoking, drinking, gastroesophageal reflux disease (GERD) frequency and severity in previous years, and history of respiratory and laryngopharyngeal disorders in the previous year. Results: The prevalence of heartburn, Regurgitation, Epigastric pain, Dyspepsia, Pharyngitis, Laryngitis, GRED Frequency, Smoking, Drinking alcohol and BMI among male and female individuals has significant (P > 0.05) with laryngopharyngeal, respiratory illnesses. The Correlation between percentage association of gastroesophageal reflux disease and laryngopharyngeal illness showed in table-3. The findings of this study were indicated a directly proportional significant (P>0.05) correlation of Pharyngitis and Laryngitis with GRED Frequency of individuals. Practical implication: Through current study health awareness can be delivered in the local population. Conclusion: In conclusion, gastroesophageal reflux disease is a substantial public health issue that affects a large portion of the adult population. The pathophysiology and etiology of gastroesophageal reflux disease are likely linked to a number of laryngopharyngeal, respiratory illnesses. Keywords: Esophagus, Gastroesophageal reflux diseases, Heartburn, Regurgitation and Retrosternal pain