Profile of Colorectal Adenocarcinoma in Dr. Soetomo Hospital Surabaya Period 2018-2022

Background: The incidence of colorectal cancer is increasing every year by about 8% with most patients in men. This cancer mostly occurs in old age above 50 years. Most colorectal cancers are of the adenocarcinoma type, which is most common on the left side of the colon. One of the determinant prognosis factors of colorectal adenocarcinoma is the depth of invasion, the deeper the correlate with invasion, the worse the prognose. Method: Descriptive research with a retrospective approach. The sample used data from histopathological examination results with a diagnosis of colorectal adenocarcinoma from surgery and biopsy material at the Anatomy Pathology Laboratory of Dr. Soetomo General Academic Hospital Surabaya for the period 2018-2022. Result: The total sample size was 143 cases with the most patients being male (60.84%) and the most age group being 51-60 (41.26%). The most common location was rectum (13.29%) with T stage (the most invasion depth was T3 (19.58%). The most common degree of differentiation was low degree (58.04%) with stage N (metastasis to lymph node) which was N0 (23.78%). Discussion: Age and lifestyle (drinking alcohol and smoking) are two of the many risk variables that affect the occurrence of colorectal cancer. The right-sided colon is the most typical site of adenocarcinoma, and it is linked to both KRAS and NRAS variables. The degree of differentiation can affect survival, although the depth of invasion and metastatic variables also affect prognosis. Conclusion: Colorectal adenocarcinoma is mostly found in men over 50 years of age with low differentiation and is most commonly located in the rectum.