e0548 Correlation between apnoea hypopnoea index and sleeping heart rate in Chinese adult

Objective To detect the correlation between apnoea-hypopnoea index (AHI) and parameters of sleeping heart rate. Method 404 subjects who experienced polysomnography (PSG) during 2005–2008 in The Third Hospital of Peking University ENT department were included. The participants were separated as obstructive sleep apnoea-hypopnoea syndrome and normal population. OSAHS patients were divided into mild, moderate and severe group according to Chinese guideline. Max sleeping heart rate (MaxHR), min sleeping heart rate (MinHR) and difference of heart rate (max minus min, dHR) were compared between groups. Result 1) MaxHR, MinHR and dHR were 92.00±13.11/min, 51.15±9.72/min and 40.84±12.30/min in OSAHS population. The three parameters in control participants were 87.40±11.82/min, 50.24±9.81/min and 37.16±12.35/min, respectively. Significant differences of MaxHR and dHR were detected between OSAHS group and control ones, besides MinHR. (pMaxHR=0.003, pdHR=0.028 and pMinHR=0.440). 2) Positive correlation were detected between AHI and MaxHR (r=0.320, p<0.001), as well as dHR (r=0.205, p<0.001). 3) Linear regression was preformed to adjusted bias induced by sex, age or other factors. Result of regression indicated that AHI was an independent factor of MaxHR and dHR. Conclusion The max sleeping heart rate and difference of sleeping heart rate was significantly high in OSAHS population. AHI was an independent risk factor of sleeping heart rate.