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Measuring coagulopathy in pediatric craniofacial surgery
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Complex cranial vault reconstruction (CCVR) for repair of
craniosynostosis is a procedure associated with high risk of bleeding
and resultant coagulopathy. The goal of this study was to describe lab
parameters in a cohort of pediatric patients undergoing CCVR and
identify if standard hematologic and coagulation laboratory results
could predict blood loss. We found that standard hematologic and
coagulation laboratory parameters predicted intraoperative and
postoperative blood loss, but provided limited mechanistic information
to improve our understanding of coagulopathy in craniofacial surgery.
Future laboratory-based studies would be useful in providing a
comprehensive model of coagulopathy in this population.
Title: Measuring coagulopathy in pediatric craniofacial surgery
Description:
Complex cranial vault reconstruction (CCVR) for repair of
craniosynostosis is a procedure associated with high risk of bleeding
and resultant coagulopathy.
The goal of this study was to describe lab
parameters in a cohort of pediatric patients undergoing CCVR and
identify if standard hematologic and coagulation laboratory results
could predict blood loss.
We found that standard hematologic and
coagulation laboratory parameters predicted intraoperative and
postoperative blood loss, but provided limited mechanistic information
to improve our understanding of coagulopathy in craniofacial surgery.
Future laboratory-based studies would be useful in providing a
comprehensive model of coagulopathy in this population.
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