Effect of Overnight Orthokeratology Lens Wear on Sleep and Quality of Life in Children Aged 8-12 Years and Relationship Between Corneal Morphology and Visual Function

Abstract It was to investigate vision, sleep, quality of life (QOL), and corneal morphology changes before and after overnight orthokeratology lens wear in myopic children aged 8–12 years. 100 myopic children were randomly divided into control group and test group, and glasses and overnight orthokeratology lens wear were worn separately. Uncorrected visual acuity, refraction, axial length, corneal endothelial cells, and corneal morphology were compared beforewear (0d), and 1 month (1mo), 3 months (3mo), and 6 months (6mo) after wear. The OQASTM II was used to evaluate visual quality, the Pittsburgh sleep quality index (PSQI) was used to evaluate sleep quality, and the QOL scale was used. Compared with 0d, there were significant differences in uncorrected visual acuity, refraction, axial length, corneal cell morphology, corneal morphology, visual quality, PSQI score, and QOL score between the control group and the test group (P < 0.05). Compared with the control group, in the test group, the uncorrected visual acuity, refraction, corneal cell variation coefficient, and QOL score at 3mo and 6mo after wear increased (P < 0.05); axial length, corneal endothelial cell density, hexagonal cell ratio, sleep onset time, sleep disorders, daytime function, PSQI, and OQAS values decreased (P < 0.05); subjective sleep quality, sleep duration, and sleep aids increased at 1mo after wear (P < 0.05). Myopic children with overnight orthokeratology lens wear can improve vision, life and sleep quality, but subjective sleep quality is reduced at early wear.