Javascript must be enabled to continue!
Melanoma arising in a hairy nevus spilus
View through CrossRef
AbstractCutaneous melanoma may develop de novo on normal skin or in contiguity with a potential melanocytic precursor. We report a 45‐year‐old man who presented with a recently developed nodule in a previously stable congenital nevus. Physical examination revealed a 10 × 18‐cm lesion with speckled lentiginous pigmentation and terminal hairs on the lower back. A 2 × 2‐cm suspicious nodule in the lesion was noted by the patient 2 months earlier. Histopathological evaluation of the nevus and the suspicious nodule revealed the characteristics of a melanocytic nevus and melanoma, respectively. It was interesting for the authors to observe terminal hairs in a lesion that was clinically ‘speckled lentiginous’ in appearance. This case report is a reminder that there may be great variation in the clinical appearance of nevus spilus, and thus dermatologists must be aware of these lesions as potential precursors of malignant melanoma.
Title: Melanoma arising in a hairy nevus spilus
Description:
AbstractCutaneous melanoma may develop de novo on normal skin or in contiguity with a potential melanocytic precursor.
We report a 45‐year‐old man who presented with a recently developed nodule in a previously stable congenital nevus.
Physical examination revealed a 10 × 18‐cm lesion with speckled lentiginous pigmentation and terminal hairs on the lower back.
A 2 × 2‐cm suspicious nodule in the lesion was noted by the patient 2 months earlier.
Histopathological evaluation of the nevus and the suspicious nodule revealed the characteristics of a melanocytic nevus and melanoma, respectively.
It was interesting for the authors to observe terminal hairs in a lesion that was clinically ‘speckled lentiginous’ in appearance.
This case report is a reminder that there may be great variation in the clinical appearance of nevus spilus, and thus dermatologists must be aware of these lesions as potential precursors of malignant melanoma.
Related Results
Precursors of skin melanoma (melanoma-sensitive nevi)
Precursors of skin melanoma (melanoma-sensitive nevi)
Interest in melanoma precursors, or melanoma-sensitive skin nevi, has not lost its relevance for many years due to the steady increase of skin melanoma morbidity in recent decades ...
A case series of congenital nevus and their various manifestations
A case series of congenital nevus and their various manifestations
A nevus is characterized by collection of partially differentiated or well-differentiated cells normally found in the skin. Some nevi are associated with disorders such as autism, ...
Assessing the Impact of Simulated Color Vision Deficiency on Ophthalmologists’ Ability to Differentiate between Choroidal Melanoma and Choroidal Nevus
Assessing the Impact of Simulated Color Vision Deficiency on Ophthalmologists’ Ability to Differentiate between Choroidal Melanoma and Choroidal Nevus
Background: Color vision deficiency (CVD) is an often-overlooked issue within the medical community, and its consequences remain insufficiently explored. We aim to evaluate how CVD...
Abstract 4342: Histological variants and sites of presentation of malignant melanoma in a resource poor setting: A histopathological review
Abstract 4342: Histological variants and sites of presentation of malignant melanoma in a resource poor setting: A histopathological review
Abstract
Background: Melanoma is a malignant tumour that arises from melanocytic cells. The incidence is increasing worldwide in white population where fair skin peo...
Abstract 1631: Cav1 is a key mediator of tumor-stromal interactions in melanoma.
Abstract 1631: Cav1 is a key mediator of tumor-stromal interactions in melanoma.
Abstract
Several lines of experimental evidence have demonstrated the importance of the tumor microenvironment in controlling melanoma tumor growth and melanoma meta...
YY1-induced lncRNA00511 promotes melanoma progression via the miR-150- 5p/ADAM19 axis
YY1-induced lncRNA00511 promotes melanoma progression via the miR-150- 5p/ADAM19 axis
Abstract
Background
Long noncoding RNAs (lncRNAs) are key regulators of oncogenic processes, and one such lncRNA is lncRNA511 (LINC00511), which is associated with breast,...
Pivotal factors associated with the immunosuppressive tumor microenvironment and melanoma metastasis
Pivotal factors associated with the immunosuppressive tumor microenvironment and melanoma metastasis
AbstractBackgroundConsidering melanoma is the deadliest malignancy among dermatoma and presently lacks effective therapies, there is an urgent need to investigate the potential mec...
Nevus Unius Lateris (NUL) in a Theree-Year-Old Child Treated by Tretinoin 0.025%, Desoxymethasone 0.25%, and Urea 20% Cream
Nevus Unius Lateris (NUL) in a Theree-Year-Old Child Treated by Tretinoin 0.025%, Desoxymethasone 0.25%, and Urea 20% Cream
Background: Linear verrucous epidermal nevus is the most frequent variant of the epidermal nevus classification. Linear verrucous epidermal nevus is characterized by the proliferat...

