MANAGEMENT OF PERIPHERAL VASCULAR MALFORMATIONS BY ABSOLUTE ALCOHOL

Objective: According to ISSVA 2014 classification, peripheral vascular malformations are divided to fast and slow flow. In spite of clear diagnosis, management is still challenging because of low rate of getting rid of lesions and high risk of complications. Endovascular management is first choice in daily practice, but cured rate is maximum about 30%. Combined treatment increases rate of success to get rid of malformations, especially surgical remvoving after endovascular management. There are many embolized materials, but absolute alcohol seem to be effective, but highly complications. Study and method: A prospective intervened study without case control. 89 patients satisfied standard are collected from 06/2016 to 06/2020. We evaluated clinical response, imaging improvement and effectiness of absolute alcoholic management. Results: Of 89 patients, female is majority with 62.9%, older than 18 is about 42.9%, mean age is 23.1. Sessions, method of approaching, volume of alcohol, combined treatment are significantly remarkable different between fast and slow flow malformations (p value = 0.021). Treatment are seem to be more effective in slow flow (p = 0.023),but fast flow malformations are curable in clinical and imaging studies. Major complications is indifferent between two groups. Conclusion: Venous malformations are majority amongst vascular malformations in our study. Because of complex scenario, difficulty of management in fast flow lesions, follow up is prolonged, volume of alcohol is increased, therapeutic sessions is repeated many times compared to slow flow. Successful treatment is higher in slow flow malformations than fast flow, but latter one is able to be cured. There are no difference between two group in field of complications. However, glycemia is negative correlation with minor complications, natremia is also reverse correlation to postoperational pain. Pain scale, symptom’s onset and APTT are positive correlations with complications. Key words: fast flow malformations, slow flow malformations, absolut alcohol, major complications, minor complications.