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A theoretical study of oleuropein derivatives as drugs
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Oleuropein is a natural product revealing a large variety of biological activity. The natural products are functionalized to increase the activity in the pharmaceutical industry. Theoretical calculations were carried out for oleuropein derivatives to display the target compound exhibiting the most biological effects. Hence, synthetic chemists are able to get inspired to synthesize the most active oleuropein derivatives. The chemical properties of oleuropein derivatives have been investigated theoretically. Gaussian method was used for quantum calculations of these compounds. The properties of compounds were presented and the utilization of these compounds in pharmaceutical industries was investigated. The quantum calculations revealed that 2H-oleuropein (3) and 4-aminobutyl-2-oleuropein (2) were unstable and were prone to react to the radical compounds.
Turkish Computational and Theoretical Chemistry
Title: A theoretical study of oleuropein derivatives as drugs
Description:
Oleuropein is a natural product revealing a large variety of biological activity.
The natural products are functionalized to increase the activity in the pharmaceutical industry.
Theoretical calculations were carried out for oleuropein derivatives to display the target compound exhibiting the most biological effects.
Hence, synthetic chemists are able to get inspired to synthesize the most active oleuropein derivatives.
The chemical properties of oleuropein derivatives have been investigated theoretically.
Gaussian method was used for quantum calculations of these compounds.
The properties of compounds were presented and the utilization of these compounds in pharmaceutical industries was investigated.
The quantum calculations revealed that 2H-oleuropein (3) and 4-aminobutyl-2-oleuropein (2) were unstable and were prone to react to the radical compounds.
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