Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
The AD Exposome
View through CrossRef
Efforts to find human genes for Alzheimer Disease and for longevity have generally neglected environmental influences. Brain aging and ADRDA may be understood in the AD Exposome framework, which includes external and endogenous interactions from embryo to old age (Finch and Kulminski 2019; Finch and Haghani 2021). Environmental factors in brain aging and longevity are as strong as common aging genes illustrated by the 15-year difference in the onset of dementia across SES (Finch 2023). Gene-environment interactions merit further attention.
International Association of Biomedical Sciences
Title: The AD Exposome
Description:
Efforts to find human genes for Alzheimer Disease and for longevity have generally neglected environmental influences.
Brain aging and ADRDA may be understood in the AD Exposome framework, which includes external and endogenous interactions from embryo to old age (Finch and Kulminski 2019; Finch and Haghani 2021).
Environmental factors in brain aging and longevity are as strong as common aging genes illustrated by the 15-year difference in the onset of dementia across SES (Finch 2023).
Gene-environment interactions merit further attention.
Related Results
Biomedical Informatics and the Digital Component of the Exposome
Biomedical Informatics and the Digital Component of the Exposome
Biomedical informatics plays a key role in the development of precision medicine and other new technology-enabled health disciplines. In this context, the exposome (defined as the ...
Climate change, human health, and the exposome: Utilizing OMIC technologies to navigate an era of uncertainty
Climate change, human health, and the exposome: Utilizing OMIC technologies to navigate an era of uncertainty
Climate change is an anthropogenic phenomenon that is alarming scientists and non-scientists alike. The emission of greenhouse gases is causing the temperature of the earth to rise...
Mediation analysis
Mediation analysis
Abstract
Understanding mechanisms between the urban environmental exposome and cognitive functioning outcomes is a key aim of the SPACE project. Structural equation ...
Exposome Signatures of Lower Back Pain Among Active Duty U.S. Army and Marine Corps Rotary Wing Pilots and Maintenance Crews
Exposome Signatures of Lower Back Pain Among Active Duty U.S. Army and Marine Corps Rotary Wing Pilots and Maintenance Crews
Abstract
Introduction
Lumbosacral pain (LBP) is common among active-duty military service members (ADSM). According to the 2019 ...
A Novel Classification Method for Adaptation Responsiveness to a 5-day
Heat Acclimation Protocol
A Novel Classification Method for Adaptation Responsiveness to a 5-day
Heat Acclimation Protocol
Purpose: To present a novel way of classifying individuals based on
their adaptive response to a 5-day heat acclimation (HA) protocol. Methods:
...
A comprehensive non-targeted analysis study of the prenatal exposome
A comprehensive non-targeted analysis study of the prenatal exposome
Recent technological advances in mass spectrometry have enabled us to screen biological samples for a very broad spectrum of chemical compounds allowing us to more comprehensively ...
Preadolescent acne
Preadolescent acne
Current data on child and preadolescent acne epidemiology, morbidity rate in different countries of the world, approaches to therapy now are presented. Modern knowledge of genetic,...
Current and Future Methodology for Quantitation and Site-Specific Mapping the Location of DNA Adducts
Current and Future Methodology for Quantitation and Site-Specific Mapping the Location of DNA Adducts
Formation of DNA adducts is a key event for a genotoxic mode of action, and their presence is often used as a surrogate for mutation and increased cancer risk. Interest in DNA addu...