Absence of New T-wave Inversion After Successful Primary Percutaneous Coronary Intervention

Abstract BACKGROUNDNew beginning of T Wave Inversion (TWI) after the primary PCI was taken as no negative T waves on the presenting ECG and considered as a new TWI case. Major Adverse Cardiac Events (MACE) which included occurrence of nonfatal myocardial infarction, cardiovascular mortality, and re-hospitalization for heart failure was taken as primary endpointThe primary aim of the study was to determine the frequency of absence of new T wave inversion (TWI) after successful Primary Percutaneous Coronary Intervention (PPCI) in patients. The secondary aim of the study was to assess the association between the development of new TWI after successful PCI and MACE after 30-days of the procedure.METHOD This 06 months prospective observational study was conducted at the Department of Interventional Cardiology at the National Institute of Cardiovascular Disease (NICVD), Karachi, Pakistan.Non-probability, Consecutive Sampling was used to collect the study sample. All patients aged between 18 to 65 years, both male and female, who presented with acute STEMI (within 12 hours of chest pain) and underwent successful primary PCI were included in this study. RESULTSA total of 310 patients were enrolled with no missing data and incomplete information was found. Out of 310, most of the study population was male (237) as compared to female (73). Non-Diabetic, Non-hypertensive, Non-Smoker, Non-Obese, and with no Family History were not statistically significant with new TWI after 30 min and 48 hrs successful PCI in acute STEMI patients. MACE after 30 days was observed to be a not statistically significant factor as well with respective with new TWI after 30 min and 48 hrs successful PCI in acute STEMI patients, however, all patients were observed to be free from MACE after 30 daysCONCLUSION Overall in our study population, we have observed new TWI frequently observed in all age groups with gender distribution and comorbid factors. Although our primary objective was straightly observed in the minimal population as absence of T wave frequency observed to be minimal.