Knowledge, Attitude and Practice Regarding Antibiotic Use and resistance Among Khartoum State Residents 2021.

Abstract Introduction: antibiotic resistance is one of the of the world must lethal health crisis affecting low- and middle-income countries, the economic burden of the issue is high.Multi- dug resistant strains are emerging, and actions are needed to counter it.Objectives: To study knowledge, attitude and practice regarding antibiotic use and resistance among Khartoum state residents.Methodology: community based cross-sectional study was conducted in Khartoum state, Sudan, residents were involved in the study were randomly selected, and the questionnaire was delivered and data about Khartoum residents’ knowledge, attitude and practice regarding antibiotic use and resistance were collected.Results: A total of 351 samples were collected, the sample included more females (58.7% vs 41.3), most of the respondents were in the 18- 25 age group, majority were students, most of the respondents had achieved university and post graduate education, most of the respondents were from Khartoum, Omdurman and then Bahri. The mean monthly income was 141759 SDGs. Majority had good knowledge regarding antibiotic use and resistance, more than 15% of respondents didn’t know that antibiotic use can result in secondary infections after killing the good bacteria. Majority of respondents had positive attitude regarding antibiotic use and resistance, except in question 15 majority of patients think antibiotics are not safe drugs. Majority of respondents had good practice regarding antibiotic use, except in question 20 where the majority Doesn’t consult in a regular basis every time before starting antibiotic.Conclusions: the study concluded that the majority of Khartoum state residents had good knowledge regarding antibiotic use and resistance and good attitude and practice regarding antibiotic use.This research is an important step in the understanding of knowledge, attitude and practice regarding antibiotic use and resistance among residents of Khartoum, its results can be used in formulation of future educational programs.Recommendations: Ongoing research studies should focus on finding the reasons behind misbehaviours and research about sensitivity patterns should be done in Sudan to formulate guidelines that help doctors to choose antibiotics for prescription in a way that minimizing the emergence of new strains of resistance bacteria.