Relation Between Hypertensive Retinopathy with Left Ventricular Hypertrophy and Proteinuria in Hypertensive Patient

Background: Hypertensive retinopathy is almost always associated with other target organ damage. Relationship of hypertensive retinopathy with left ventricular hypertrophy (LVH) and proteinuria was inconclusive in previous studies.Objective: To assess the relation between Left Ventricular Hypertrophy and Proteinuria in Hypertensive Patient with Retinopathy in Tertiary Care Hospital.Methods: This is a cross-sectional observational study and conducted at the Department of Medicine and Cardiology in Dhaka Medical College Hospital. Total 100 hypertensive retinopathy patients were included in the study. Following informed written consent, physical examination, relevant investigations were done. In all cases, Ethical issues were maintained properly and collected data were analysed by SPSS 20.Results: Among 100 participants, mean age was 57.15 (±12.989 SD) years [age range 29-85] and 61% were male & 39% were female. Mean value of Systolic (SBP) and Diastolic Blood pressure (DBP) in Grade (G)-1, G-2 and G-3 hypertension were 150.8 (± 5.4) & 94 (± 2.6) mm Hg, 170.3 ± 4.9 & 101.0 ± 4.7 mm Hg and 188.0 ± 7.0 & 102.6 ± 6.5 mm Hg respectively and it is significantly associated with severity of LVH (p value < 0.001 in both SBP & DBP). Proteinuria is also associated with severity of hypertension (p <0.001) but there were no association of Hypertensive retinopathy with LVH and proteinuria (p value 0.32 and 0.27 respectively).Conclusion: LVH & Proteinuria is associated with severity of Hypertension but Hypertensive retinopathy is not associated with LVH and proteinuria, though further large cohort is recommended for final comment.