Wavefront Guided LASIK with a High-Resolution Aberrometer Induces Less Higher-Order Aberration than Early Custom LASIK

Abstract Background: The use of 'high-resolution' aberrometer wavefront-guided LASIK system offers the theretical advantages. To date there have been a few papers that proved the clinical superiority of the 'high-resolution' wavefront-guided LASIK. The purpose of this present study was to To evaluate the surgical outcomes of wavefront-guided laser in-situ keratomileusis (LASIK) via a high-resolution aberrometer to treat myopic refractive error. Methods: This study involved 51 eyes of 26 consecutive patients (high-resolution group) who underwent wavefront-guided LASIK from 2012 to 2015 via high-resolution aberrometer and excimer laser surgical unit at the Baptist Eye Institute, Kyoto, Japan and who were followed for 6-months postoperative. Postoperative outcomes were compared with our historical control data (early custom group) from 2002 to 2007 (51 eyes of 26 patients) treated with the same correction amount. Measured parameters included Visual acuity (VA), spherical equivalent refractive error (SER), higher-order aberration (HOA), and contrast sensitivity (CS).Results: In the high-resolution group and the early custom group, the mean SER was -5.86±2.57 diopters (D) and -5.99±2.52D, respectively, and the mean patient age was 33.8±9.2 and 34.3±6.9 years, respectively. LogCS of 18 cycles-per-degree (cpd) change was more satisfactory in the high-resolution group than in the early custom group. Postoperative spherical aberration change in the high-resolution group was significantly lower than that in the control group (P<0.05). Decrease of induced spherical aberration produced a positive effect on the post LogCS of 18 cpd.Discussion: The latest wavefront-guided LASIK induced less HOAs than early custom LASIK, and although similar VA and refractive precision findings were observed, the high-resolution group tended to acquire better visual function post surgery.